منابع مشابه
Natural Product Research: Formerly Natural Product Letters
New sesquiterpenoid derivatives from Solanum septemlobum with cytotoxicities Lei Zhang, Hai-Qing Lin, Gui-Sheng Li, Xi-Dian Yue & ShengJun Dai a School of Pharmaceutical Science, Yantai University, Yantai 264005, P.R. China b State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical Coll...
متن کاملNatural Product Research: Formerly Natural Product Letters
Anthemis wiedemanniana essential oil prevents LPS-induced production of NO in RAW 264.7 macrophages and exerts antiproliferative and antibacterial activities in vitro Filomena Conforti a , Federica Menichini a , Carmen Formisano b , Daniela Rigano b , Felice Senatore b , Maurizio Bruno c , Sergio Rosselli c & Sezgin Çelik d a Department of Pharmaceutical Sciences , University of Calabria , via ...
متن کاملNatural product and natural product derived drugs in clinical trials.
There are a significant number of natural product (NP) drugs in development. We review the 100 NP and NP-derived compounds and 33 Antibody Drug Conjugates (ADCs) with a NP-derived cytotoxic component being evaluated in clinical trials or in registration at the end of 2013. 38 of these compounds and 33 ADCs are being investigated as potential oncology treatments, 26 as anti-infectives, 19 for th...
متن کاملNatural Product Hybrids
this review highlights several classes of natural product hybrids. First, structural hybrids emanating from different biosynthetic pathways exemplified by the polyketide peptide alkaloid anachelin are discussed. Another class is the so-called functional hybrids, where different functions of natural products are hybridized. the conjugate between nostocarboline and the well-known antibacterial ag...
متن کاملNatural Product Synthesis
The Lycopodium alkaloids are a family of structurally complex natural products, which have provoked long-term interests in their total syntheses because of their unique and fascinating architectures and potential biological activities. In particular, fawcettimine-type Lycopodium alkaloids, such as fawcettimine (1) and fawcettidine (2) (Scheme 1), have attracted broad attention from the syntheti...
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ژورنال
عنوان ژورنال: Current Opinion in Chemical Biology
سال: 2013
ISSN: 1367-5931
DOI: 10.1016/j.cbpa.2013.07.005